YWHAB Antibody is a Rabbit Polyclonal antibody against YWHAB. This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

Target	14-3-3 Protein Beta/Alpha (YWHAB)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 150-246 of human 14-3-3 alpha/beta.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P31946 (UniProt, ExPASy)
UniProt Secondary AC	A8K9K2, E1P616
UniProt Entry Name	1433B_HUMAN
Gene Symbol	YWHAB
GeneID	7529
NCBI Accession	NP_003395.1
KEGG	hsa:7529
String	9606.ENSP00000361930
Molecular Weight	Calculated MW: 28 kDa Observed MW: 28 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 14-3-3 Protein Beta/Alpha (YWHAB)